DOES NSAID EXACERBATED RESPIRATORY DISEASE (N-ERD) ACCOMPANYING SEVERE ASTHMA AFFECT BIOLOGICAL TREATMENT RESPONSE? EFFICACY OF OMALIZUMAB AND MEPOLIZUMAB IN N-ERD

Introduction: Non-steroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (N-ERD) accompanies severe asthma in about 15% of the patients essie pink glove and may adversely affect the prognosis.Omalizumab and mepolizumab are biologics used in patients with severe asthma.The objective of this study is to assess the respiratory improv

Isocyanide-based multicomponent reactions (IMCRs) allow the construction of relatively complex molecules through a one-pot synthesis.The combination of IMCRs in a consecutive or vince camuto fiori gift set sequential fashion further extends the complexity of the molecules obtained.Herein, we report the efficient application of this approach to the

Economic sanctions as an economic war have challenged the Islamic system.And the economy is with infidel countries whose political policy is in opposition to the embargoes.The issue at hand is what are the jurisprudential barriers and permissions of these types of agreements and how are they analyzed in dealing with each other? The descriptive-anal

Introduction.This article discusses types of attitudes towards the disease in women with different durations of somatization disorders.The results from this study can be useful for achieving successful therapeutic interaction between secondary care medical specialists and patients with somatization disorders.Changes in disharmonious attitudes towar

Abstract In the Global South, young people who use drugs (YPWUD) are exposed to multiple interconnected social and health harms, with many low- and middle-income countries enforcing racist, prohibitionist-based drug policies that generate physical and structural violence.While harm reduction coverage for YPWUD is suboptimal globally, in low- and mi